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Metabolic Health
Saxenda® (liraglutide) is a prescription GLP-1 receptor agonist used for chronic weight management in adults with obesity or overweight with weight-related health conditions. It works by helping control appetite, reduce calorie intake, and support long-term weight loss when combined with diet and exercise. Saxenda is administered as a once-daily subcutaneous injection and is designed to help patients feel fuller for longer, making it easier to reduce food intake and manage body weight.
Saxenda (liraglutide) is a prescription weight-loss injection used for chronic weight management. It is recommended for:
Adults with obesity (BMI ≥30)
Overweight patients (BMI ≥27) with conditions like diabetes or hypertension
It should always be used alongside a reduced-calorie diet and increased physical activity.
Saxenda belongs to a class of drugs called GLP-1 receptor agonists. It works by:
Reducing appetite
Increasing feelings of fullness
Slowing stomach emptying
This helps patients eat less and gradually lose weight.
Saxenda is injected once daily under the skin.
Week 1: 0.6 mg
Week 2: 1.2 mg
Week 3: 1.8 mg
Week 4: 2.4 mg
Week 5 onward: 3 mg (maintenance dose)
👉 Gradual dose increase helps reduce side effects like nausea.
Inject under the skin of the abdomen, thigh, or upper arm
Use a new needle for each injection
Do not share your pen with others
Rotate injection sites daily
Check that the solution is clear and colorless
Most side effects occur early and improve over time:
Nausea
Vomiting
Diarrhea or constipation
Loss of appetite
💡 Tip: Eating smaller meals can help reduce nausea.
Seek medical attention if you experience:
Severe abdominal pain (possible pancreatitis)
Neck swelling or hoarseness (thyroid concerns)
Signs of gallbladder problems
⚠️ Saxenda may increase the risk of thyroid tumors in rare cases.
Do NOT use Saxenda if you have:
Personal or family history of medullary thyroid carcinoma (MTC)
Multiple endocrine neoplasia syndrome type 2 (MEN 2)
Allergy to liraglutide
Use caution when combining Saxenda with:
Insulin or sulfonylureas (risk of low blood sugar)
Oral medications (absorption may be delayed)
Store unused pens in a refrigerator (2–8°C)
After first use:
Keep at room temperature or refrigerated
Use within 30 days
Do not freeze
Use Saxenda daily at the same time
Follow a healthy diet and exercise plan
Stay hydrated
Do not stop treatment without consulting your doctor
Weight loss may take several weeks
Patients may notice appetite reduction within a few days, but significant weight loss usually occurs over several weeks.
Yes, it can be used long-term if it is effective and well tolerated under medical supervision.
If you miss a dose, take it as soon as possible. Do not take extra doses to make up for a missed one.
No. Saxenda is not insulin; it works on appetite regulation, not blood sugar replacement.
Saxenda (liraglutide) is an effective option for weight management when combined with lifestyle changes. Proper dosing, administration, and awareness of side effects are essential for safe and successful treatment.
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